Over-imaging in uncomplicated low back pain: a 12-month audit of a general medical unit.

Rego MH, Nagiah S, Internal Med J Dec. 2016

Abstract
Low back pain is frequently encountered in hospitals and is a leading cause of disability, often involving costly imaging that exposes a patient to radiation. A retrospective 12-month audit at a South Australian hospital evaluated the frequency, modality and appropriateness of imaging in patients with low back pain.
Results showed that the general medical unit was unnecessarily ordering imaging in 40% of patients who exhibited NO indications warranting such a procedure.

A standardised protocol is required to preventing clinicians from requesting imaging solely for the purposes of self-reassurance, patient reassurance or fear of litigation.

Study Refutes Link Between Strokes, Chiropractic Care

(NewsUSA) Dec 2016

There have been some high-profile stories of stroke after a visit to a chiropractor several days before to relieve neck pain.


The theory is being refuted by research done this year by a team of neurosurgeons at the Penn State Hershey Medical Center. They performed what they described as “a systematic review and meta-analysis of published data” to determine whether there’s a direct correlation between the manipulation performed by doctors of chiropractic — manual adjustments widely acknowledged to relieve muscle-related pain — and a condition called cervical artery dissection (CAD) in which a small tear opens in the artery walls of the neck.
That’s important since such a tear can result in a stroke should a blood clot form and later break free to block a blood vessel in the brain.

The team’s conclusion? “There is no convincing evidence to support a causal link between chiropractic manipulation and CAD.”
CAD is actually quite rare. It’s been estimated that it annually strikes only two to three people, per 100,000 of the population, and various epidemiologic studies through the years suggest that strokes can occur at an equal rate whether sufferers are under chiropractic or other medical care for the headaches and neck pain it often produces.
As for chiropractic care in general, it’s worth remembering that — after the Centers for Disease Control and Prevention urged doctors last March to avoid prescribing potentially addictive prescription painkillers in the face of mounting deaths — a slew of health experts joined the chorus of those who’d already been praising chiropractic as a safe and effective treatment for neck, mid back, and lower back pain.

Mobilization-Therapy vs. Motion-Therapy

Having been an advocate of ATM-2 therapy for nearly 13 years I have been encouraged to recognize how instability (hyper-mobility or excessive motion in-the-neutral zone of a motion segment) differs from hypo-mobility in several key ways. Most Chiropractic procedures have as their implicit “finding” a segment in need of mobilization. However the difficulty with our ubiquitous concept (at the core of virtually all techniques) is that hypo-mobility has no objectifier i.e. no valid or reliable tests to prove its existence. Recent videofluoroscopy studies suggest hyper, hypo & paradoxical motion are “random” occurrences within the spine…if you observe the spine consistently under precise conditions the motion-segments fluctuate (this is not the case with severe degenerative or anatomically fused segments of course) so the “when and how” of “mobilization” remains elusive.
Hyper-mobility however can be clinically validated via force-closure/muscle-contraction tests. Muscles brace and stiffen the spine and as such will buttress motion and stop the pain-invoking shear. The “when & how” of “motion-therapy” is more secure.

An investigation into the effects of a unilaterally applied lumbar mobilisation technique on peripheral sympathetic nervous system activity in the lower limbs.

Perry J Green A. Man Ther Dec 2008

Abstract
Physiotherapeutic management of lumbar disorders often utilises specific segmental joint mobilisation techniques; however, there is only limited evidence of any neurophysiological effects and much of this has focused on the cervical spine and upper limbs. This study used a unilaterally applied lumbar spinal mobilisation technique and explored its effects on the peripheral NS (SNS) of the lower limbs. 45 normal healthy males were assigned to one of three experimental groups (control, placebo or treatment.
A unilaterally applied P-A mobilisation to the left L4/5 zygopophyseal joint). SNS activity was determined by recording skin conductance (SC) obtained from lower limb electrodes.
Results indicated that there was a significant change in SC from baseline levels (13.5%) that was specific to the side treated for the treatment group during the intervention period (compared to placebo and control conditions). This study provides preliminary evidence that a unilaterally applied P-A mobilisation technique performed at a rate of 2 Hz, to the left L4/5 lumbar zygopophyseal joint results in side-specific peripheral SNS changes in the lower limbs.

Effect of spinal decompression on the lumbar muscle activity and disk height in patients with herniated intervertebral disk.

Kang JI et al Journal of PT sci Nov 2016

Abstract: This study was conducted to clarify the difference in therapeutic effects between traction and decompression therapies, and their clinical therapeutic significance.

Subjects and Methods:
The subjects were 31 patients aged 35 to 50 years who had unilateral or bilateral lumbar and radicular leg pain. An intervention program was implemented in 31 patients with lumbar herniated intervertebral disks. For the experimental group, 15 subjects were randomly selected to receive decompression therapy and trunk stabilization exercise. For the control group, 16 subjects were randomly selected to receive static traction therapy and trunk stabilization exercise.

Results: Activities of the rectus abdominis, transverse abdominis, and external oblique muscles increased significantly in both groups. However, the activity of the erector spine muscle decreased, which was the only significant change in muscle activity among those of the other muscles in both groups. The disk herniation index in the experimental group decreased significantly in comparison with that in the control group, and the difference in the change in disk herniation index between the groups was significant.

Conclusion: Decompression therapy was demonstrated to be more effective clinically than conventional traction therapy as an intervention method for disk disease.

Maximum Pain on Visual Analog Scales in Spinal Disorders.

Spine J. 2016 Dec 6.

Behrend CJ Schönbach et al

BACKGROUND CONTEXT:
Determining pain intensity is largely dependent on the patient’s report.
PURPOSE:
To test the hypothesis that patients initially reporting 10/10 pain on visual analog scales (VAS) would experience symptom improvement to a degree similar to patients reporting milder pain.
RESULTS:
The proportion of patients with identifiable secondary gain was higher (P=0.001) than among those with submaximal pain. Patients whose pain scores improved dramatically (i.e. at least 4 points on VAS), tend to be older (p=0.001), to less often have secondary gain from their disease (p=0.007), and to have a negative current smoking status (p=0.002). Patients whose pain remained 10/10 during the course of treatment smoked more frequently (p=0.016).
CONCLUSIONS:
Our analysis supports the need to consider the influence of secondary gain on the patients’ reported VAS pain scores. Maximum pain seems to be a more acute phenomenon with some likelihood to significantly improve.

Reliability of Diagnosis and Clinical Efficacy of Cranial Osteopathy: A Systematic Review.

Guillaud A et al 

CONTEXT:

In 2010, the World Health Organization released benchmarks for training in osteopathy in which they considered cranial osteopathy as an important osteopathic skill. However, the evidence supporting the reliability of diagnosis and the efficacy of treatment in this field appears scientifically weak and inconsistent.

There was no restriction regarding the type of disease.

SEARCH RESULTS:

In our electronic search we found 1280 references concerning reliability of diagnosis studies plus four references via our complementary strategy. 

RESULTS:

For reliability studies, our analysis leads us to conclude that the diagnostic procedures used in cranial osteopathy are unreliable in many ways. 

CONCLUSION:

Our results demonstrate, consistently with those of previous reviews, that methodologically strong evidence on the reliability of diagnostic procedures and the efficacy of techniques and therapeutic strategies in cranial osteopathy is almost non-existent.

Effects of dietary restriction on adipose mass and biomarkers of healthy aging in human.

J Aging Letteri-Barbora et al Nov. 2016

Abstract
In developing countries the rise of obesity and obesity-related metabolic disorders, such as cardiovascular diseases and type 2 diabetes, reflects the changes in lifestyle habits and wrong dietary choices. Dietary restriction (DR) regimens have been shown to extend health span and lifespan in many animal models including primates. Identifying biomarkers predictive of clinical benefits of treatment is one of the primary goals of precision medicine. To monitor the clinical outcomes of DR interventions in humans, several biomarkers are commonly adopted. However, a validated link between the behaviors of such biomarkers and DR effects is lacking at present time. Through a systematic analysis of human intervention studies, we evaluated the effect size of DR (i.e. calorie restriction, very low calorie diet, intermittent fasting, alternate day fasting) on health-related biomarkers. We found that DR is effective in reducing total and visceral adipose mass and improving inflammatory cytokines profile and adiponectin/leptin ratio. By analysing the levels of canonical biomarkers of healthy aging, we also validated the changes of insulin, IGF-1 and IGFBP-1,2 to monitor DR effects. Collectively, we developed a useful platform to evaluate the human responses to dietary regimens low in calories.

Of 20,376 Lumbar Discectomies, 2.6% of Patients Readmitted within 30 Days: Surgical Site Infection, Pain, and Thromboembolic Events are the Most Common Reasons for Readmission.

Spine 2016
Webb ML1, Nelson SJ

OBJECTIVE:
As an initial effort to address readmissions after lumbar discectomy, reasons for hospital readmission are identified and discussed.
SUMMARY OF BACKGROUND DATA:
Lumbar discectomy is a commonly performed procedure. The Affordable Care Act codifies penalties for hospital readmissions.
RESULTS:
Of 20,376 lumbar discectomies, 533 patients (2.62%) were readmitted within 30 days of surgery. The most common reasons for readmission were surgical site infections (n = 130, 0.64% of all discectomies, 24.4% of all readmissions), followed by pain issues (n = 89, 0.44%, 16.7%), and thromboembolic events (43, 0.21%, 8.1%). Overall time to readmission was 13.0 days ± 8.0 days.
CONCLUSIONS:
Surgical site infection, postoperative pain, and thromboembolic events were the most common reasons for readmission after lumbar discectomy. These findings identify potential areas for quality improvement initiatives.

Neurochemical changes in patients with chronic low back pain detected by proton magnetic resonance spectroscopy: A systematic review.

Zhao X1, Xu M1, 

BACKGROUND:
Low back pain is a highly prevalent health problem around the world, affecting 50% to 85% of people at some point in life. The purpose of this systematic review is to summarize the previous proton magnetic resonance spectroscopy studies on brain chemical changes in patients with chronic low back pain (CLBP).

RESULTS:
The results showed that compared to controls, CLBP patients showed reductions of 1) N-acetyl-aspartate (NAA) in the dorsolateral prefrontal cortex (DLPFC), right primary motor cortex, left somatosensory cortex (SSC), left anterior insula and anterior cingulate cortex (ACC); 2) glutamate in the ACC; 3) myo-inositol in the ACC and thalamus; 4) choline in the right SSC; and 5) glucose in the DLPFC.


CONCLUSION:
This review provides evidence for alterations in the biochemical profile of the brain in patients with CLBP, which suggests that biochemical changes may play a significant role in the development and pathophysiology of CLBP and shed light on the development of new treatments for CLBP.